The serum level of HMGB1 (high mobility group box 1 protein) is preferentially high in drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms.
نویسندگان
چکیده
denominator of TEN development. A single or multiplier effect by idiosyncratic, dose-related or drug-interactive reactions of phytochemicals or contaminants might be involved in the development of TEN in these patients. The objective evaluation by the Naranjo adverse drug reaction (ADR) probability scale calculated a possible ADR by the herbal remedy in cases 1 and 3 and a probable cause in case 2. In all cases, the TEN-specific algorithm for epidermal necrolysis (ALDEN) confirmed a possible cause of herbal remedies in TEN developement.
منابع مشابه
Drug reaction with eosinophilia and systemic symptoms syndrome in a patient taking phenytoin and levetiracetam: a case report
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ورودعنوان ژورنال:
- The British journal of dermatology
دوره 171 6 شماره
صفحات -
تاریخ انتشار 2014